Lisa woke up this morning saying, "I feel like I've been hit by a train."  Today was the day that the chemo effects really hit.  By mid-morning, it had lessened to the point where she changed it to feeling like she'd been hit by a truck, and that carried through most of the evening.   Hopefully that won't continue into the weekend.  Next week is her "off" week, so we're both looking forward to that.